Diabetes .. Risks of the use of basal insulin and sulfonyl urea

 

NEW YORK (Reuters Health) – A new study has warned of serious side effects of two of the most common drugs used by type 2 diabetics, basal insulin and sulfonil urea, which increase the risk of heart attack, stroke, heart failure and amputation, British .

The study, conducted by researchers at the University of Northwestern, America, that the drugs of sulfonyl Urea and basal insulin, which are described to patients with diabetes, if the failure of metformin in lowering blood sugar enough or cause intolerable side effects such as diarrhea or muscle pain or vomiting, Cause serious side effects.

One in every 37 diabetics who take basal insulin will have a cardiovascular disease over the next two years, making it twice as likely to be affected, one study said.

One out of every 103 patients who take sulfonyl urea will have a 24-month heart attack or stroke.

The study was conducted by researchers at Northwestern University under the leadership of Dr. Matthew O’Brien, Assistant Professor of General Medicine.

Dr. O’Brien, head of the research team, said the results of the study called for a quantum leap in the treatment of type 2 diabetes.

“People should know if the drugs they are taking to treat their diabetes can lead to serious cardiovascular damage,” he said.

The researchers said in the journal JAMA Network Open that heart disease is the leading cause of morbidity and death among patients with type 2 diabetes.

During the first study of its kind, the researchers looked at data from 132,727 type 2 diabetics who started processing the second line.

Although the list of second-line drugs includes six drugs, basal insulin and sulfonil urea constitute 60% of the drugs prescribed by physicians for type 2 diabetics.

Baseline insulin is designed to release the hormone slowly throughout the day, unlike continental insulin, which acts quickly and needs to be eaten before meals.

Sulfonyl urea acts by stimulating cells in the pancreas to produce more insulin and help make the hormone work more efficiently.